A Personalized Web Application to Predict Changes in Knee Pain among Patients with Osteoarthritis Participating at the GLA:D® program

92
Nicht eingeplant
20m
Von-Melle-Park 4

Von-Melle-Park 4

Poster

Beschreibung

GLA:Dai (https://apps.cosy.bio/gladai) is a web application for predicting individualized changes in knee pain for patients considering enrollment with the GLA:D® program (Good Life with osteoArthritis in Denmark). The statistical model is based on self-reported patient information to predict the individual change in pain intensity (VAS scale 0 to 100) from before to after GLA:D® enrollment. We select important variables from 51 candidates using the "Gini impurity" and clinical reasoning. We trained a random forest regression model and compared it against predicting the mean change in pain. Our individualized model yields a 7% improvement, contributes to personalized healthcare by enabling patients to estimate their change in pain intensity, and allows for more data-driven treatment decisions.

Keywords

osteoarthritis,
prediction,
pain Intensity,
web-based tool,
exercise therapy

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Autor

Mahdie Rafiei (Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany)

Co-Autoren

Herr Supratim Das Herr Jan Baumbach (Director of the Institute for Computational Systems Biology University of Hamburg) Frau Linda Baumbach (Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Germany)

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